The key to a good tweak is simple, do it at the right time and don’t blow up what exists.
Switching tires that you have a hunch might do better on the last lap – good tweak.
Wanting to replace the engine on the last lap – bad tweak.
The key is doing it at the right time and not putting yourself into such a hole that you can’t recover if it doesn’t work it out.
That’s why it’s a tweak and not a change.